Introduction: Induction of labour denotes the artificial initiation of regular uterine contractions before spontaneous onset of labour with progressive dilatation and effacement of cervical and subsequent vaginal delivery of the baby. Labour induction is usually indicated when benefits of delivery to the mother or fetus outweigh the potential risks of continuing the pregnancy. Labour usually starts spontaneously in most of pregnant women at or near-term pregnancy and result in vaginal deliveries.

Aims and objectives: Aim of the study is to evaluate efficacy of misoprostol in comparison with dinoprostone for labour induction in term pregnant women.

Materials and methods: The study was carried out over 100 pregnant women admitted to the labour ward beyond 37 weeks of gestation, requiring induction of labour for various medical and obstetrical indications, in the department of Obstetrics and Gynaecology, Silchar medical college & hospital from 1^st June 2021 to 1^st June 2022. The participants were divided into two Groups-I and Group-II. Group-I, choosing the patients randomly. In Group-I, 50 patients received 25 µg Misoprostol per vaginally and in Group-II, 50 patients received Dinoprostone gel 0.5 mg endocervically.

Results: In Group-I, 25 cases (50%), Bishop score were ≥10/13 at 8 hrs. after induction of labour and in Group-II, 23 cases (46%), Bishop score were ≥10/13, (P= 0.3702). In Group-I, 43 cases had taken

Induction to delivery interval less in misoprostol group (mean ± S.D) 14.36±4.39 hours than dinoprostone group 16.68±4.43 hrs.  (P=0.085). There was no significant difference in neonatal complication and NICU admission among both the study groups.

Conclusion: From the present study, it can be concluded that the tab. Misoprostol 25 µg pervaginal is more effective in comparison to Dinoprostone 0.5 mg endocervical for induction of labour with respect to the induction to onset of labour interval and induction to delivery interval.

Keywords: Misoprostol, Dinoprostone, Induction of labour.

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